Dr. Kirino qualified with an MD from the Yokohama City University School of Medicine, Japan in 2001. After the internship, he went on to study for a Ph.D. in Department of Rheumatology at Yokohama City University Graduate School of Medicine (Prof. Yoshiaki Ishigatsubo lab). Under the supervision of Dr. Mitsuhiro Takeno, he investigated heme degrading pathways in Behçet's disease. From 2009 to 2012, he was trained as a postdoctoral fellow at Dr. Daniel Kastner lab in US National Institutes of Health, NHGRI. Along with Dr. Elaine Remmers and Prof. Ahmet Gül, he participated in genome-wide association studies of Behçet's disease, which led to the discovery of gene-gene interaction between HLA-B*51 and ERAP1 in Behçet's disease. After returning to Yokohama City University, as Assistant Prof., he studied the epidemiology of Behçet's disease. He reported that clinical phenotypes are changing in Japan during past 30 years. Also, he is studying the function of GWAS-identified loci. His team recently identified that CCR1 and IL10 eQTL effects in polarized macrophages in Behçet's disease. He received a Promotion Award from Japan College of Rheumatology in 2015. Kirino is currently a Councilor of Japan College of Rheumatology, and the member of Behçet's Disease Research Committee, the Ministry of Health, Labor, and Welfare of Japan (Chairperson Prof. Nobuhisa Mizuki).